The 1+ Million Genomes (1+MG) Framework provides guidelines for the implementation of the 1+MG initiative, which is enabling secure access to genomics and the corresponding clinical data across Europe for better research, personalised healthcare and health policy making.
Learn more about the Framework and related projects
1+MG Framework foundations
Core guidance for building 1+MG compatible genomic data sharing Nodes in Europe
Legal, ethics and governance
Explore governance documentation including consent models, privacy safeguards and legal frameworks
Technical infrastructure
Find information on the standards, APIs and reference implementations to build a 1+MG Node
Data and metadata
Find resources on data models, minimal metadata, quality and inclusion standards
Healthcare integration and sustainability
Guidance for preparing health systems to adopt genomics, including a maturity model and long-term sustainability planning
Applying the 1+MG Framework
Design principles and real-world applications of the Framework across Europe
Use cases
Information on the scientific and clinical questions driving our development
External alignment
Discover how the 1+MG infrastructure is connected across Europe and beyond
National implementation
See how countries are integrating and adapting the Framework
Projects
The 1+MG Framework is built from the outputs of the 1+MG project family, including B1MG, B1MG+, GDI (Genomic Data Infrastructure) and Genome of Europe. These projects have developed the foundational components, infrastructure and policy coordination needed to realise the 1+MG Framework.